Thimerosal Content in Some US Licensed Vaccines

updated 10-04-2001

Vaccine

Brand Name

Manufacturer

Thimerosal Concentration1

Mercury
 ug/0.5 ml

Date Approved

or Changed

pg in 2001 PDR

Anthrax

Anthrax vaccine

BioPort Corporation

0

0

    

DTaP

Acel-Imune

Tripedia
Certiva
Infanrix

Wyeth-Ayerst

Aventis Pasteur
Baxter
GlaxoSmithKline

.01%

*
.01%
0

25

--*
25
0

no longer produced
03-28-00
07-29-98 – no longer produced
01-29-97

1653
787



3100

DTwP

All Products

 

.01%

25

    

DT

All Products

 

.01%

25

    

Td

All Products

 

.01%

25

    

TT

All Products

 

.01%

25

    

DTwP-Hib

Tetramune

Wyeth-Ayerst

.01%

25

no longer produced

  

Hib

ActHIB/Omni HIB
ProHIBiT
TriHIBit
HibTITER   multi-dose
                    single dose
PedvaxHIB liquid(2)
COMVAX(3)

Aventis Pasteur
Aventis Pasteur
Aventis Pasteur
Wyeth-Ayerst
Wyeth-Ayerst
Merck
Merck

0
.01%
*
.01%
0
0
0

0
25
*
25
0
0
0

09-27-96
no longer produced



03-98 (web)
10-02-96

767

787
1662
1662
1985
1893

Hepatitis A

Havrix
Vaqta adult/pediatric

GlaxoSmithKline
Merck

0
0

0
0


03-29-96

3094
2036

Hepatitis B

Engerix-B preservative free
Engerix-B 
Recombivax HB preservative free
Recombivax HB 

GlaxoSmithKline
GlaxoSmithKline
Merck

Merck

*

.005%
0

.005%

*

12.5
0

12.5

03-28-00

08-27-99

3087

2016

Hep A-B

Twinrix

GlaxoSmithKline

0

0

05-11-2001

  

Influenza

All products in U.S.

 

.01%

25

    

IPV

IPOL

Aventis Pasteur

0

0

  

778

Lyme

LYMErix

GlaxoSmithKline

0

0

12-21-98

3108

Meningococcal

Menomune A, C, AC and A/C/Y/W-135

Aventis Pasteur

*

*

  

783

MMR

MMR-II

Merck

0

0

  

1952

Measles

Attenuvax

Merck

0

0

  

1882

OPV

Orimune

Wyeth-Ayerst

0

0

no longer produced

  

Pneumococcal

Prevnar
Pnu-Imune 23
Pneumovax 23

Wyeth-Ayerst
Wyeth-Ayerst
Merck

0
.01%
0

0
25
0

02-17-00

1986

1673
1671
1994

Rabies

Rabies Vaccine Adsorbed
RabAvert
IMOVAX

Bioport Corporation
Chiron
Aventis Pasteur

.01%
0
0

25
0
0

03-18-88
10-20-97
07-91 (PDR)


1100
776

Rotavirus

Rotashield

Wyeth-Ayerst

0

0

08-31-98

withdrawn 10-15-99

  

Typhoid

Vivotef Berna

Berna

0

0

04-97 (PDR)

933

Typhoid Fever

Typhim Vi
Typhoid vaccine

Aventis Pasteur
Wyeth-Ayerst

0
0

0
0

06-95 (PDR)

02-09-94 (PDR)

794

3467

Varicella

Varivax

Merck

0

0

03-17-95

2038

Yellow Fever

YF-Vax

Aventis Pasteur

0

0

05-96 (PDR)

796

___ - shaded text indicates vaccines no longer in production

1.    A concentration of 1:10,000 is equivalent to a 0.01% concentration. Thimerosal is approximately 50% Hg by weight.   A 1:10,000 concentration contains 25 micrograms of Hg per 0.5 mL.
2. A previously marketed lyophilized preparation contained 0.05% thimerosal.
3. COMVAX is not approved for use under 6 weeks of age because of decreased response to the Hib component.

* This product should be considered equivalent to thimerosal-free products.  This vaccine may contain trace amounts (<0.3 mcg) of mercury left after post-production thimerosal removal; these amounts have no biological effect.   JAMA 1999;282(18) and JAMA 2000;283(16).

Information provided by http://www.vaccinesafety.edu/thi-table.htm